2-phenylquinolin-4-carboxylic-acid ester.



' o-224st.

No Drawing.

UNITED STATES PA PENT ()FFICE.

LUDWIG TAUB, OF ELBERFELD, GERMANY, ASSIGN OR TO FARBENFAIBlRJIKEN VORM. FRIEDR. BAYER -e z 00., OF ELBERFELD, GERMANY, A CORPORATION OF GERMANY.

Z-PHENYLQUINOLIN-4-CARBOXYLIC-ACID ESTER.

. My invention relates to the manufacture and productionof the ethyl ester of 2- phenyl q'uinolin at carboxylic' acid having most probably the formula:

o'ooc m V Specification of Letters Patent.

Applicationfiled December 16, 1911. Serial No. 666,213.

tion of the 2-'phenylquinolin-4-carboxylic acid; The following example may illustrate the process, the parts being by weight :-In a vessel provided with a reflux condenser 249 parts of 2-phenylquinolin-4-carboxylic acid are heated to boiling during 6-8" hours with ten times its quantity of a concentrated solution of hydrochloric acid in ethyl alcohol. The alcohol is distilled off and the oily residue is Washed until neutral with Water.

The herein described ethyl ester of 2 p11enylquinolin-L-carboxylic acid crystallizing from alcohol in whitish tasteless prisms melting at 6l62 0.; being soluble in organicsolvents; forming salts with acids; and being a remedy against gout, substantially as described. y In testimony whereof I have hereunto set my hand in the presence of two subscribing Witnesses. V

LUDWVIG TAUB. [L. s.] Witnesses: I

HELEN NUFEB, A. NUFER.

Patented A pr.-9, 1912; 

